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Synthetic Cannabinoids are illegal in New Zealand, it is classed as a category A managed drug.[198] The brand new Zealand Parliament passed a law in July 2013 banning the sale of legal highs in dairies and supermarkets, but letting some "minimal risk" drugs to continue for being marketed by means of speciality certified outlets.
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PB-22 and 5F-PB-22 had been the initial synthetic cannabinoids to incorporate a quinoline substructure and an ester linkage. These compounds are assumed to happen to be synthesized With all the intention of constructing a synthetic cannabinoid prodrug, which website might make improvements to absorption and confound detection. Ester bonds are quickly biodegradable via spontaneous or endogenous, nonspecific esterase hydrolysis, which has been commonly Employed in medicinal chemistry for making ester prodrugs.
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